There are " systems " for mattress cleaning, which consist of ..................a vacuum cleaner with a u/v light attached and a spray.
You can purchase a water filtration vacuum from Denis Rawlins which will capture and hold everything in water.............this really gives 100% suction constantly and returns nothing to the room.
Alltec's Promite will kill dustmites and protect the fabric.
There are are other products which will do a similar job, but I've used the ones I mention . It will cost you about £300 for the machine and enough chemical to do several jobs.