it all depends on how fast you want to make water and if you have somewhere to keep a large storage tank.
if you want instant water then as already said 2 di vessels is best, the reason for 2 is that you can use them inline and the 1st vessel can be used until it isn't purifying the water anymore, therefore getting maximum use from the resin, whereas with 1 large vessel you still have to change the resin as soon as the tds goes up.