Series - The waste has much higher tds, so the following membrane will get smashed and have to buy a new ine more frequently but you should technically save on waste (not much to write home about imo)
Parallell - even wear though the membranes as each is getting the same (mains so lower) tds, but when it does come to new membrane time, chances are you'll have to get all 3
Personally, i prefer in parrallel as the advantages of series is minimal imo